<%@LANGUAGE="JAVASCRIPT" CODEPAGE="1252"%> Mold Misery - Pathogenicity of Mycotoxins - Hemolytic Mycotoxins


 

 

 

 

Pathogenicity
 

 

One of the theories of mold is that only certain molds produce toxic metabolites.  Of these, the trichothecenes are the ones most discussed but there are also hemolysins, chemicals that cause rupturing of red blood cells and sometimes severe anemia.

Before trying to say anything on the subject of mycotoxicity, I want to reiterate something I have said before:  mold can and will and does destroy blood.  In my observations of live blood, it can achieve this in at least three ways:

  1. By devouring the red blood cells while in the vegetative state.  In this case, the RBCs travel through the hypha where they are exposed to acids and enzymes.  At the end of this journey, the formerly discrete RBCs are liquefied and presumably also predigested.  It is pointless to get into a debate over this phenomenon until one has actually seen this in a microscope.
  2. By spraying something on substances that causes a nearly total dematerialization of the cells.  It is unclear to me whether the mold "eats" these substances or merely causes their rapid decomposition.
  3. By releasing a chemical that causes very rapid hemolysis.  The interesting feature of this activity is that the shells of the RBCs do not disintegrate and are not used as food by the mold.  Therefore, this side effect of mold exposure occurs independently of what is generally called the vegetative state.
This is a photomicrograph of red blood cells that have lysed. The curious fact about such occurrences is that the blood does not decompose further, at least not on the slide.  It remains microbe-free and frozen in time.

There is another factor that can also lead to serious blood loss and that is a consequence of the colonization and vegetative behavior of mold.  This can lead to tissue perforation and hemorrhaging.  It can also result in two entirely separate physiological developments:

  1. The appearance of what seem to be growths, such as tumors; and
  2. Loss of tissue that varies from demyelination of nerve sheaths to tiny fissures and large holes where all the tissue has been either eaten or dematerialized by the mold or the mycotoxins.

If all this were not enough, it is clear that the mycotoxins cause damage to tissues, including vital organs.  This can interfere with the functions of the affected tissues and organs and lead to organ failure.  Some of the mycotoxins are scarring and cause sclerosis whereas others interfere with body chemistry and organ integrity.

All in all, this is a grave picture and one that is nearly always underestimated by all but the best informed patients and a small number of health care professionals who are risking their reputations by stating matters that are nearly always met with resistance by the uninitiated.

 

Many blessings,

Ingrid Naiman
21 October 2006

 

 

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